The Department of Biological and Biochemical Sciences and Immunochemistry section, University of Pardubice, was established in 1996. The group has been involved in the frame of research activities in proteome analysis of proteins specialized in bioaffinity chromatography and immunochemistry. As main topics of research interest we have to mention the preparation of a bioaffinity matrix with oriented immobilized antibodies, enzymes, ligands for highly specific determination, isolation and purification of target proteins, glycoproteins and for enzyme modification.